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Pfizer selected Denmark as the site of the largest vaccine registry study ever undertaken, demonstrating how Europe can attract world-leading life sciences investment when the right conditions are in place. Beginning in 2024, Pfizer partnered with researchers at the Center for Translational Cardiology and Pragmatic Randomized Trials at Herlev-Gentofte Hospital in Copenhagen to assess whether its respiratory syncytial virus vaccine could reduce hospitalisations in adults. Denmark’s innovation-friendly environment, national digital mailbox eBoks and world-class health registries enabled researchers to invite almost the entire adult population to take part, helping recruit more than 500,000 participants. Study materials were made available online, allowing participants to provide informed consent from home, while health registries supported comprehensive tracking and analysis. This milestone shows how strong public-private collaboration and a supportive policy framework can help Europe deliver clinical research at scale and improve health outcomes for citizens. Read the full story on Invested in Europe. 

How can Europe strengthen its digital resilience while remaining open to the partnerships that drive AI innovation? On Wednesday, 17 June, Malte Lohan, CEO, AmCham EU, addressed this at a conference organised by the Cypriot Presidency of the Council of the EU in Nicosia, Cyprus. Discussions focused on how Europe can build a more resilient digital ecosystem while remaining an attractive destination for investment and innovation. Mr Lohan underlined that secure supply chains and trusted partnerships are essential to Europe’s AI competitiveness. He also highlighted the role of US businesses as committed partners in helping Europe build and compete globally, while stressing the need for balanced policies that strengthen resilience and give companies the confidence to invest in Europe.

This week the European Commission unveiled its Tech Sovereignty Package. While the Package’s energy proposals mark a significant step forward for EU energy resilience, the Cloud and AI Development Act (CADA) proposal overlooks the reality of global technology supply chains and introduces significant legal uncertainty and fragmentation for businesses.

The central question for the Tech Sovereignty Package is how to build resilience without undermining competitiveness. Concerns around overdependence on a limited number of providers, the risk of external disruption to service continuity and the long-term position of the EU’s digital industries are all legitimate. However, greater sovereignty will only be sustainable if it is built on a competitive, diverse and innovative digital ecosystem. The technologies that underpin the global digital economy are developed through highly international supply chains, with innovation spread across multiple markets.

Viewed through this lens, the individual proposals in the Package vary in the extent to which they reinforce resilience while preserving openness and competitiveness. In particular, the proposed CADA risks discriminating against providers that rely on global supply chains – both those based in Europe and those in third countries – even where they offer superior resilience.

‘An origin-based approach is too blunt for such a complex global market’, said Malte Lohan, CEO of the American Chamber of Commerce to the European Union, commenting on the Package.

‘A more credible path to achieving greater resilience and control in such an interconnected landscape is to define sovereignty in terms of outcomes: secure and reliable technologies, customer choice, strong safeguards against undue interference and a business environment that supports investment and growth. That points to a risk-based framework where the EU is open to working with trusted partners. This trust should be assessed on the basis of objective standards rather than origin alone’, Mr Lohan added.

Last year alone, US technology firms operating in Europe and their supply chains supported €1.0 trillion in EU GDP, equivalent to 5.4% of total output. The scale of this contribution underscores the need for the EU to preserve an open environment with legal clarity and proportionality in any restrictions or safeguards that would impact commercial operations.

The Package’s Strategic Roadmap for Digitalisation and AI in energy is a positive step that could help unlock the benefits of digitalisation for Europe’s energy needs, enabling faster and more flexible grids. Digitalisation provides new opportunities to strengthen the reliability and resilience of energy systems. If executed well, the roadmap could support the growing demand of Europe’s digital and AI sectors for low-carbon energy.

Ultimately, the importance of the Tech Sovereignty Package extends well beyond the technology sector itself. Manufacturers, healthcare and life sciences, financial services, mobility, energy and retail all increasingly depend on access to advanced digital technologies to innovate and compete. For the Tech Sovereignty Package to support these sectors, it must ensure companies in Europe continue to benefit from economic openness.